Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | TTR | P02766 | 1/20 | 0.83 |
| ▸ | PPOX | P50336 | 1/20 | 0.83 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acifluorfen SCHEMBL29448829 | 0.91 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29445767 | 0.91 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL38929 | 0.91 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL8028079 | 0.91 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL3228873 | 0.91 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL1830812 | 0.90 | TDP1 (0.98) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL10556004 | 0.90 | TDP1 (0.98) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL3690938 | 0.90 | TDP1 (0.98) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10786867 | 0.87 | TDP1 (0.81) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL10542053 | 0.87 | TDP1 (0.92) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405805-A | ACIFLUORFEN, XYLENE EXTRACTION | RHONE-POULENC, INC. (US) | 1983-09-20 | — | — | US | claimed |
| EP-0706993-B1 | Method of purifying acifluorfen | BASF CORP (US) | 1998-03-04 | — | — | EP | disclosed |
| EP-0706993-A1 | Method of purifying acifluorfen | BASF Corporation (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5446197-A | Dissolving in 1,2-dichlorobenzene solvent, recrystallization | BASF CORPORATION (US) | 1995-08-29 | — | — | US | disclosed |
| US-4874846-A | Process for the preparation of aryloxybenzoic acids containing a sulfonamide group | RHONE-POULENC AGROCHIMIE S.A. (FR) | 1989-10-17 | — | — | US | disclosed |
| US-4780128-A | Herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-25 | — | — | US | disclosed |
| US-4738711-A | POST- AND PREEMERGENCE HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-04-19 | — | — | US | disclosed |
| US-4465508-A | Diphenyl ether herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-14 | — | — | US | disclosed |
| EP-0023392-B1 | DIPHENYL ETHER COMPOUNDS, AND HERBICIDAL COMPOSITIONS AND PROCESSES UTILISING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-06 | — | — | EP | disclosed |
| US-4332611-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0023392-A2 | Diphenyl ether compounds, and herbicidal compositions and processes utilising them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-02-04 | — | — | EP | disclosed |