Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | PPOX | P50336 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31118239 | 0.90 | MEN1 (0.55) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10656466 | 0.84 | KMT2A (0.42) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10668736 | 0.83 | TDP1 (0.64) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10663135 | 0.82 | TDP1 (0.41) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL31118305 | 0.81 | ALDH1A1 (0.37) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10775569 | 0.81 | KMT2A (0.40) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10671720 | 0.81 | TDP1 (0.61) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL9768812 | 0.80 | MEN1 (0.72) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL11147168 | 0.80 | MEN1 (0.72) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10552727 | 0.80 | TDP1 (0.76) | TDP1MEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780128-A | Herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-25 | — | — | US | disclosed |
| US-4738711-A | POST- AND PREEMERGENCE HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-04-19 | — | — | US | disclosed |
| US-4465508-A | Diphenyl ether herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-14 | — | — | US | disclosed |
| EP-0023392-B1 | DIPHENYL ETHER COMPOUNDS, AND HERBICIDAL COMPOSITIONS AND PROCESSES UTILISING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-06 | — | — | EP | disclosed |
| EP-0023392-A2 | Diphenyl ether compounds, and herbicidal compositions and processes utilising them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-02-04 | — | — | EP | disclosed |