Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | ACP1 | P24666 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | PRNP | P04156 | 2/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675093 | 0.92 | CYP2C9 (0.71) | CYP2C9ACP1SMN1; SMN2KDM4EPDE10A | |
| SCHEMBL10673820 | 0.86 | CYP2C9 (1.00) | CYP2C9ACP1SMN1; SMN2KDM4EPDE10A | |
| SCHEMBL10683012 | 0.84 | CYP2C9 (0.60) | CYP2C9ACP1SMN1; SMN2KDM4EPDE10A | |
| Hydrochloric Acid SCHEMBL10673862 | 0.83 | CYP2C9 (0.59) | CYP2C9ACP1SMN1; SMN2KDM4EPDE10A | |
| SCHEMBL9380982 | 0.82 | RXFP1 (0.53) | CYP2C9SMN1; SMN2KDM4ERXFP1TSHR | |
| SCHEMBL10671292 | 0.77 | PDE10A (0.58) | CYP2C9SMN1; SMN2KDM4EPDE10ALMNA | |
| Hydrochloric Acid SCHEMBL26649569 | 0.75 | PDE10A (0.56) | CYP2C9SMN1; SMN2KDM4EPDE10ALMNA | |
| Hydrochloric Acid SCHEMBL10676746 | 0.75 | CYP2C9 (0.69) | CYP2C9SMN1; SMN2KDM4ELMNATSHR | |
| SCHEMBL10674581 | 0.74 | PDE10A (0.55) | CYP2C9SMN1; SMN2KDM4EPDE10ALMNA | |
| SCHEMBL10679321 | 0.74 | LMNA (0.68) | CYP2C9SMN1; SMN2KDM4EPDE10ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |