Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10721387 | 0.90 | SMPD1 (0.48) | SMPD1KDM4EALDH1A1ABCB1LTB4R | |
| SCHEMBL9829599 | 0.85 | SMPD1 (0.51) | SMPD1KDM4EABCB1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL9830009 | 0.85 | SMPD1 (0.51) | SMPD1KDM4EABCB1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL10672717 | 0.84 | SMPD1 (0.50) | SMPD1KDM4EABCB1TP53CYP3A4 | |
| SCHEMBL9828934 | 0.84 | SMPD1 (0.49) | SMPD1KDM4EABCB1TP53CYP3A4 | |
| SCHEMBL10668003 | 0.79 | SMPD1 (0.41) | SMPD1ALDH1A1ABCB1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL9831956 | 0.78 | SMPD1 (0.47) | SMPD1KDM4EABCB1CYP3A4MAPT | |
| Oxalic Acid SCHEMBL9831824 | 0.78 | SMPD1 (0.46) | SMPD1KDM4EALDH1A1ABCB1MAPT | |
| Hydrochloric Acid SCHEMBL9829155 | 0.78 | SMPD1 (0.50) | SMPD1ABCB1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9831196 | 0.78 | SMPD1 (0.49) | SMPD1ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |