Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 8/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9830009 | 0.99 | SMPD1 (0.51) | SMPD1ABCB1CYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9831196 | 0.89 | SMPD1 (0.49) | SMPD1ABCB1CYP3A4BLMPMP22 | |
| SCHEMBL9829147 | 0.87 | SMPD1 (0.51) | SMPD1ABCB1CYP3A4CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL10672717 | 0.86 | SMPD1 (0.50) | SMPD1ABCB1CYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9832211 | 0.86 | SMPD1 (0.50) | SMPD1ABCB1CYP3A4BLMPMP22 | |
| SCHEMBL9828934 | 0.85 | SMPD1 (0.49) | SMPD1ABCB1CYP3A4MAPTKDM4E | |
| Oxalic Acid SCHEMBL10673157 | 0.85 | SMPD1 (0.49) | SMPD1ABCB1CYP3A4MAPTKDM4E | |
| SCHEMBL9828526 | 0.82 | SMPD1 (0.42) | SMPD1ABCB1 | |
| Hydrochloric Acid SCHEMBL9829234 | 0.82 | SMPD1 (0.41) | SMPD1ABCB1 | |
| Hydrochloric Acid SCHEMBL9829155 | 0.80 | SMPD1 (0.50) | SMPD1ABCB1CYP3A4BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | claimed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | claimed |