Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 3/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677829 | 0.78 | HPGD (0.53) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL31529344 | 0.78 | LMNA (0.69) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL10675207 | 0.78 | LMNA (0.60) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL29245619 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL10680469 | 0.76 | HPGD (0.51) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL955714 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL6534175 | 0.73 | NR2E1 (0.55) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL6534179 | 0.73 | NR2E1 (0.55) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6534370 | 0.73 | LMNA (0.50) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6534372 | 0.73 | LMNA (0.50) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |