Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676138 | 0.92 | RAB9A (0.58) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10677526 | 0.91 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10682406 | 0.90 | RAB9A (0.49) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL11024159 | 0.86 | MAOB (0.48) | RAB9AMAPTSMN1; SMN2HPGDNPC1 | |
| SCHEMBL10681255 | 0.82 | HPGD (0.62) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10683857 | 0.82 | L3MBTL1 (0.41) | RAB9AMAPTSMN1; SMN2HPGDNPC1 | |
| SCHEMBL10678399 | 0.82 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10673583 | 0.81 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10678053 | 0.80 | SUCNR1 (0.41) | MAPTHPGDTDP1ATM | |
| SCHEMBL10675474 | 0.80 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792570-A | 3- and 4-biphenyloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |