Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899396 | 0.74 | UGT2B7 (0.37) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL4400746 | 0.64 | PTGS2 (0.38) | TRPA1 | |
| SCHEMBL19510243 | 0.63 | SMN1; SMN2 (0.33) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL15061484 | 0.63 | UGT2B7 (0.33) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL19500827 | 0.63 | SMN1; SMN2 (0.33) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL19500828 | 0.63 | SMN1; SMN2 (0.33) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL5702612 | 0.62 | CYP3A4 (0.36) | ALDH1A1CYP3A4MAPTTRPA1 | |
| SCHEMBL12468945 | 0.62 | CYP3A4 (0.32) | ALDH1A1CYP3A4MAPT | |
| SCHEMBL23868612 | 0.60 | ALDH1A1 (0.52) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL29394941 | 0.60 | ALDH1A1 (0.52) | ALDH1A1MEN1CYP3A4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282643-A2 | Use of pharmaceutical compositions comprising cyclohexane derivatives in the treatment or prevention of peptic ulcers | THE GREEN CROSS CORPORATION (JP) | 1988-09-21 | — | — | EP | disclosed |