Ethyl Fumarate

Ethyl Fumarate

SCHEMBL1067488

C=CC=CC(=C)C(=O)OC.CCOC(=O)C=CC(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.57
ALDH1A1 P00352 5/20 0.35
MAPT P10636 8/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 3/20 0.34
MDM2 Q00987 2/20 0.34
MDM4 O15151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Fumarate SCHEMBL1068462 0.86 HCAR2 (0.55) HCAR2ALDH1A1MAPTLMNAMDM2
Ethyl Fumarate SCHEMBL1066994 0.80 HCAR2 (0.67) HCAR2ALDH1A1MAPTKDM4ETDP1
Acrylic Acid SCHEMBL17746693 0.80 LMNA (0.39) HCAR2ALDH1A1LMNAALOX15RECQL
SCHEMBL28915231 0.80 HCAR2 (0.64) HCAR2ALDH1A1MAPTLMNAMDM2
Ethyl Fumarate SCHEMBL2521076 0.79 HCAR2 (0.83) HCAR2ALDH1A1MAPTLMNAMDM2
SCHEMBL21667491 0.79 ALDH1A1 (0.42) HCAR2ALDH1A1MAPTKDM4ETDP1
SCHEMBL250949 0.79 ALDH1A1 (0.42) HCAR2ALDH1A1MAPTKDM4ETDP1
Acrylic Acid SCHEMBL17746661 0.79 HCAR2 (0.40) HCAR2ALDH1A1MAPTLMNANPSR1
SCHEMBL250740 0.78 ALDH1A1 (0.42) HCAR2ALDH1A1MAPTLMNANPSR1
Ethyl Fumarate SCHEMBL17768305 0.78 HCAR2 (0.95) HCAR2MAPTLMNAMDM2MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208257-B2 Electron beam curable toners and processes thereof XEROX CORPORATION (US) 2007-04-24 US claimed
US-20050287464-A1 Electron beam curable toners and processes thereof XEROX CORPORATION 2005-12-29 US claimed
EP-1610186-B1 Image forming process XEROX CORP (US) 2011-01-05 EP disclosed
US-7208257-B2 Electron beam curable toners and processes thereof XEROX CORPORATION (US) 2007-04-24 US disclosed
US-20050287464-A1 Electron beam curable toners and processes thereof XEROX CORPORATION 2005-12-29 US disclosed
EP-1610186-A2 Electron beam curable toners and processes thereof Xerox Corporation (US) 2005-12-28 EP disclosed