Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661020 | 0.84 | AOC3 (0.54) | MTNR1AMTNR1BAOC3L3MBTL1TSHR | |
| SCHEMBL17295959 | 0.81 | MTNR1A (0.58) | MTNR1AMTNR1BAOC3L3MBTL1TSHR | |
| SCHEMBL10928081 | 0.80 | AOC3 (0.48) | AOC3L3MBTL1PKMSLC6A2SLC6A4 | |
| SCHEMBL3398813 | 0.79 | MAOB (0.48) | MTNR1AMTNR1BAOC3L3MBTL1TSHR | |
| SCHEMBL9392741 | 0.74 | MTNR1A (0.58) | MTNR1AMTNR1BAOC3L3MBTL1TSHR | |
| SCHEMBL24925773 | 0.73 | ABCB11 (0.67) | MTNR1AMTNR1BAOC3L3MBTL1TSHR | |
| SCHEMBL18793790 | 0.73 | ABCB11 (0.67) | MTNR1AMTNR1BAOC3L3MBTL1TSHR | |
| SCHEMBL22785842 | 0.73 | AOC3 (0.66) | MTNR1AMTNR1BAOC3L3MBTL1TSHR | |
| SCHEMBL20738720 | 0.73 | ABCB11 (0.67) | MTNR1AMTNR1BAOC3L3MBTL1TSHR | |
| SCHEMBL16419134 | 0.73 | AOC3 (0.66) | MTNR1AMTNR1BAOC3L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788187-A | ANTISECRETORY AND ANTIULCEROGENIC AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4745110-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-05-17 | — | — | US | disclosed |
| US-4743600-A | ANTIULCER, ANTISECRETORY | RORER PHARMACEUTICAL CORPORATION (US) | 1988-05-10 | — | — | US | disclosed |
| US-4692445-A | ANTISECRETORY, ANTIULCEROGENIC AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| US-4647559-A | ANTISECRETORY AND ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1987-03-03 | — | — | US | disclosed |
| US-4639442-A | ANTIULCER | WILLIAM H. RORER, INC. (US) | 1987-01-27 | — | — | US | disclosed |
| US-4638001-A | ANTISECRETORY, ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0182815-A4 | BENZOCYCLOBUTENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES. | RORER INTERNAT OVERSEAS INC (US) | 1986-10-14 | — | — | EP | disclosed |
| EP-0182815-A1 | BENZOCYCLOBUTENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1986-06-04 | — | — | EP | disclosed |
| US-4588719-A | ANTISCERETORY AGENTS, ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1986-05-13 | — | — | US | disclosed |
| WO-1985005032-A1 | BENZOCYCLOBUTENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1985-11-21 | — | — | WO | disclosed |