Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | LSS | P48449 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ESRRB | O95718 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631252 | 0.95 | L3MBTL1 (0.70) | L3MBTL1GAAMAOBESR1MAPT | |
| Hydrochloric Acid SCHEMBL5412869 | 0.93 | L3MBTL1 (0.68) | L3MBTL1GAAMAOBESR1MAPT | |
| SCHEMBL9360319 | 0.89 | GAA (0.71) | L3MBTL1GAAMAOBMAPTALDH1A1 | |
| SCHEMBL8126082 | 0.87 | RARB (0.63) | ESR1BCHEACHELSSPOLB | |
| SCHEMBL14287626 | 0.87 | L3MBTL1 (0.73) | L3MBTL1GAAMAOBMAPTALDH1A1 | |
| SCHEMBL8137583 | 0.84 | MAPT (0.68) | L3MBTL1ESR1MAPTALDH1A1BCHE | |
| SCHEMBL6057420 | 0.83 | ESR1 (0.59) | GAAESR1MAPTALDH1A1BCHE | |
| SCHEMBL1981044 | 0.81 | PKM (0.62) | ESR1MAPTALDH1A1BCHEACHE | |
| SCHEMBL5151604 | 0.81 | L3MBTL1 (0.70) | L3MBTL1GAAMAOBMAPTALDH1A1 | |
| SCHEMBL13139921 | 0.81 | L3MBTL1 (0.70) | L3MBTL1GAAMAOBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764533-A | ANTITUMOR | KLINGE PHARMA GMBH (DE) | 1988-08-16 | — | — | US | disclosed |