Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863591 | 0.85 | MEN1 (0.42) | MEN1KMT2AGAATDP1ATM | |
| Hydrochloric Acid SCHEMBL3700024 | 0.82 | NPY4R (0.36) | KMT2ANPY4RNPY1RPOLB | |
| SCHEMBL10676657 | 0.82 | TDP1 (0.42) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL27484587 | 0.82 | MEN1 (0.40) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL27484588 | 0.82 | MEN1 (0.40) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL27810936 | 0.81 | C3AR1 (0.37) | MEN1KMT2AGAANPY4RNPY1R | |
| SCHEMBL27468052 | 0.81 | MEN1 (0.39) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL27468053 | 0.81 | MEN1 (0.39) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL604855 | 0.80 | MEN1 (0.45) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL604856 | 0.80 | MEN1 (0.45) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9387185-B2 | N-ω-hydroxy-L-arginine derivatives for the treatment of diseases | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2016-07-12 | — | — | US | disclosed |
| US-20120123111-A1 | Nª -Hydroxy-L-Arginine Derivatives for the Treatment of Diseases | CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL (DE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123111-A1 | Nª -Hydroxy-L-Arginine Derivatives for the Treatment of Diseases | ARG2, ARG1, NOS2 | MEN1 2465/4885KMT2A 1003/4885GAA 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.