Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220343 | 0.85 | ALDH1A1 (0.50) | HTTMAPTALDH1A1GAAKDM4E | |
| SCHEMBL15353098 | 0.79 | HTT (0.38) | HTTMAPTLMNAGAAMEN1 | |
| SCHEMBL6155679 | 0.74 | ALDH1A1 (0.42) | HTTMAPTLMNAALDH1A1GAA | |
| SCHEMBL9184970 | 0.72 | MAPT (0.42) | MAPTLMNAALDH1A1GAAMEN1 | |
| SCHEMBL11790909 | 0.71 | MAPT (0.38) | HTTMAPTALDH1A1GAAKDM4E | |
| SCHEMBL354474 | 0.71 | ALDH1A1 (0.48) | HTTMAPTLMNAALDH1A1GAA | |
| SCHEMBL9391999 | 0.70 | MAPT (0.36) | HTTMAPTLMNAALDH1A1GAA | |
| SCHEMBL15353097 | 0.70 | HTT (0.39) | HTTMAPTLMNAALDH1A1GAA | |
| SCHEMBL11789560 | 0.69 | CYP1A2 (0.45) | MAPTCYP1A2ALDH1A1GAAKDM4E | |
| SCHEMBL30099690 | 0.69 | ALDH1A1 (0.55) | MAPTLMNAALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762830-A | 5-(azolyloxyphenylcarbamoyl)barbituric acid derivatives as anthelmintics | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| US-4753940-A | PARASITICIDE, ANTHELMINTIC | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| US-4753944-A | INHIBITING THROMBOXANE SYNTHETASE | AMERICAN CYANAMID COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| US-4670441-A | PARASITICIDES | CIBA-GEIGY CORPORATION (US) | 1987-06-02 | — | — | US | disclosed |