Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354474 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10KDM4EHTT | |
| SCHEMBL14441609 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10KDM4EHTT | |
| SCHEMBL10677017 | 0.74 | HTT (0.48) | ALDH1A1LMNAHSD17B10KDM4EHTT | |
| SCHEMBL28929071 | 0.71 | TSHR (0.47) | ALDH1A1LMNAHSD17B10KDM4EMAPT | |
| SCHEMBL12994228 | 0.71 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10KDM4EMAPT | |
| SCHEMBL22897261 | 0.70 | ALDH1A1 (0.38) | ALDH1A1HSD17B10KDM4EHTTMAPT | |
| SCHEMBL16625947 | 0.70 | TSHR (0.39) | ALDH1A1LMNAHSD17B10KDM4EHTT | |
| SCHEMBL220343 | 0.69 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHTTMAPT | |
| SCHEMBL2653688 | 0.69 | TSHR (0.53) | ALDH1A1LMNAKDM4EMAPTTSHR | |
| SCHEMBL18382542 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242395-B1 | BENZOIC ACID ESTERS OF OXAZOLIDINONES HAVING A HYDROXYACETYLPIPERAZINE SUBSTITUENT | UPJOHN CO (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1242395-A1 | BENZOIC ACID ESTERS OF OXAZOLIDINONES HAVING A HYDROXYACETYLPIPERAZINE SUBSTITUENT | PHARMACIA & UPJOHN COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1242417-A1 | OXAZOLIDINONES HAVING A SULFOXIMINE FUNCTIONALITY AND THEIR USE AS ANTIMICROBIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| US-20010046987-A1 | Oxazolidinones having a sulfoximine functionality | PHARMACIA & UPJOHN COMPANY | 2001-11-29 | — | — | US | disclosed |
| US-6281210-B1 | Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent | PHARMACIA & UPJOHN COMPANY | 2001-08-28 | — | — | US | disclosed |
| WO-2001046185-A1 | OXAZOLIDINONES HAVING A SULFOXIMINE FUNCTIONALITY AND THEIR USE AS ANTIMICROBIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |
| WO-2001044212-A1 | BENZOIC ACID ESTERS OF OXAZOLIDINONES HAVING A HYDROXYACETYLPIPERAZINE SUBSTITUENT | PHARMACIA & UPJOHN COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010046987-A1 | Oxazolidinones having a sulfoximine functionality | OXA1L, SULT1A1, SULT1E1 | ALDH1A1 491/4885LMNA 4780/4885HSD17B10 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.