SCHEMBL10677463

SCHEMBL10677463

CCCN(CCC)C(=S)CCCc1nnnn1C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 1/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10676600 0.93 ALDH1A1 (0.33) DAGLACA12CA1CA2CA9
SCHEMBL10677938 0.91 CA12 (0.37) CA12CA1CA2CA9
SCHEMBL10673821 0.89 DAGLA (0.31) DAGLA
SCHEMBL10675141 0.88 DAGLA (0.32) DAGLA
SCHEMBL10678037 0.85 ALDH1A1 (0.34)
SCHEMBL10673832 0.82 DAGLA (0.36) DAGLA
SCHEMBL10969646 0.82 ALDH1A1 (0.32)
SCHEMBL10676385 0.81 DAGLA (0.32) DAGLA
SCHEMBL10673900 0.79 HTR1A (0.31) DAGLA
SCHEMBL10676030 0.78 HSD17B10 (0.34) DAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4766120-A ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1988-08-23 US disclosed
US-4663323-A Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-05-05 US disclosed
EP-0035046-B1 NOVEL TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-10-02 EP disclosed
US-4540703-A Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1985-09-10 US disclosed
EP-0035046-A1 Novel tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1981-09-09 EP disclosed