Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 4/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683013 | 0.96 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL10677070 | 0.90 | KDM4E (0.51) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL10677865 | 0.84 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL10673312 | 0.83 | PDE10A (0.54) | KDM4EDHODHLMNASMN1; SMN2PDE10A | |
| SCHEMBL10769477 | 0.82 | MOK (0.52) | ALDH1A1KDM4EHPGDMAPTDHODH | |
| Hydrochloric Acid SCHEMBL10682090 | 0.81 | MOK (0.51) | ALDH1A1KDM4EHPGDMAPTDHODH | |
| Hydrochloric Acid SCHEMBL10673221 | 0.81 | ACP1 (0.51) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL10672513 | 0.80 | KDM4E (0.60) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL10674581 | 0.79 | PDE10A (0.55) | ALDH1A1KDM4EDHODHLMNASMN1; SMN2 | |
| SCHEMBL9988793 | 0.79 | DHODH (0.53) | ALDH1A1KDM4EHPGDMAPTDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |