SCHEMBL10769477

SCHEMBL10769477

CCCN(CCC)C(=O)CCc1cc(-c2ccccc2)nc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MOK Q9UQ07 3/20 0.52
KDM4E B2RXH2 5/20 0.50
LMNA P02545 3/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
MAPT P10636 2/20 0.50
DHODH Q02127 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.47
PDE10A Q9Y233 1/20 0.47
TACR3 P29371 5/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TACR2 P21452 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10682090 0.99 MOK (0.51) MOKKDM4ELMNAALDH1A1HPGD
Hydrochloric Acid SCHEMBL10677070 0.89 KDM4E (0.51) KDM4ELMNAALDH1A1HPGDMAPT
SCHEMBL10683013 0.83 ALDH1A1 (0.53) MOKKDM4ELMNAALDH1A1HPGD
SCHEMBL10679146 0.82 ALDH1A1 (0.49) MOKKDM4ELMNAALDH1A1HPGD
SCHEMBL10671292 0.80 PDE10A (0.58) KDM4ELMNADHODHPOLBSMN1; SMN2
SCHEMBL10676850 0.80 TSHR (0.48) MOKKDM4ELMNAALDH1A1HPGD
Hydrochloric Acid SCHEMBL26649569 0.79 PDE10A (0.56) KDM4ELMNADHODHPOLBSMN1; SMN2
SCHEMBL10509237 0.78 KDM4E (0.55) KDM4ELMNADHODHPOLBSMN1; SMN2
SCHEMBL10677865 0.77 KDM4E (0.54) MOKKDM4ELMNAALDH1A1HPGD
SCHEMBL5072358 0.77 MOK (0.51) MOKKDM4ELMNAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0210084-A1 Amides, processes for their preparation and medicaments containing them RHONE-POULENC SANTE (FR) 1987-01-28 EP disclosed