Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680332 | 0.90 | GABRA2 (0.35) | — | |
| SCHEMBL10678734 | 0.83 | GABRA2 (0.38) | — | |
| SCHEMBL10682416 | 0.81 | GABRA2 (0.33) | MAPT | |
| SCHEMBL10675390 | 0.76 | XPO1 (0.31) | XPO1 | |
| SCHEMBL10676174 | 0.76 | GABRA2 (0.37) | — | |
| SCHEMBL10681975 | 0.76 | GABRA2 (0.40) | — | |
| SCHEMBL10676569 | 0.76 | MAPT (0.36) | MAPTXPO1 | |
| SCHEMBL9774866 | 0.75 | GABRB3 (0.31) | — | |
| SCHEMBL9581399 | 0.74 | GABRB3 (0.35) | — | |
| SCHEMBL9592432 | 0.74 | GABRA2 (0.33) | XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | claimed |
| US-4725607-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-16 | — | — | US | disclosed |
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | disclosed |