Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685692 | 0.90 | MEN1 (0.65) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL10679842 | 0.90 | MEN1 (0.65) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL10682674 | 0.88 | MEN1 (0.67) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL6712892 | 0.87 | MEN1 (0.71) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL10679257 | 0.86 | MEN1 (0.46) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL10809502 | 0.85 | KDM4E (0.56) | KCNH2POLBTOP2ATOP2BKDM4E | |
| SCHEMBL10683425 | 0.84 | MEN1 (0.63) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL10679862 | 0.84 | MEN1 (0.74) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL8438107 | 0.83 | ALDH1A1 (0.49) | KCNH2POLBTOP2ATOP2BKDM4E | |
| SCHEMBL10575715 | 0.82 | MEN1 (0.67) | MEN1KMT2AKCNH2CACNA1FPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284935-A1 | 5-Substituted quinolone- and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1988-10-05 | — | — | EP | claimed |
| EP-0284935-A1 | 5-Substituted quinolone- and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1988-10-05 | — | — | EP | disclosed |