Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687112 | 0.94 | RARB (0.46) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL10691667 | 0.91 | RARB (0.38) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL757405 | 0.91 | RARB (0.52) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL3839248 | 0.82 | HAO1 (0.43) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL14157557 | 0.77 | RARB (0.49) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL15082362 | 0.77 | RARB (0.49) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL15266487 | 0.75 | RARB (0.56) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL441670 | 0.75 | RARB (0.56) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL3156466 | 0.74 | RARB (0.43) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL7650224 | 0.74 | ALDH1A1 (0.44) | RARBRARGRARARXRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270124-A2 | Cycloalkane derivatives and anti-peptic ulcer compositions containing same | THE GREEN CROSS CORPORATION (JP) | 1988-06-08 | — | — | EP | disclosed |