Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679352 | 0.91 | RARB (0.47) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL10687112 | 0.86 | RARB (0.46) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL757405 | 0.82 | RARB (0.52) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL10679423 | 0.81 | RARB (0.33) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL3839248 | 0.72 | HAO1 (0.43) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL11040039 | 0.68 | TRPA1 (0.37) | ALDH1A1MAPTTRPA1ALOX15 | |
| SCHEMBL14157557 | 0.67 | RARB (0.49) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL15082362 | 0.67 | RARB (0.49) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL15266487 | 0.65 | RARB (0.56) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL441670 | 0.65 | RARB (0.56) | RARBRARGRARARXRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270124-A2 | Cycloalkane derivatives and anti-peptic ulcer compositions containing same | THE GREEN CROSS CORPORATION (JP) | 1988-06-08 | — | — | EP | disclosed |