Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24723377 | 0.88 | KDM4E (0.70) | HTR1ACYP2D6KMT2AMTNR1AMTNR1B | |
| SCHEMBL4619391 | 0.84 | CYP2D6 (0.64) | HTR1ACYP2D6KMT2AMTNR1AMTNR1B | |
| SCHEMBL3024961 | 0.83 | KDM4E (0.75) | HTR1ACYP2D6KMT2AMTNR1AMTNR1B | |
| SCHEMBL4889276 | 0.83 | MTNR1A (0.70) | HTR1ACYP2D6KMT2AMTNR1AMTNR1B | |
| SCHEMBL10671995 | 0.82 | MTNR1A (0.58) | HTR1AKMT2AMTNR1AMTNR1BHTR2B | |
| SCHEMBL3018752 | 0.82 | MTNR1A (0.70) | HTR1ACYP2D6KMT2AMTNR1AMTNR1B | |
| SCHEMBL5085972 | 0.80 | KMT2A (0.65) | HTR1ACYP2D6KMT2AMTNR1AMTNR1B | |
| SCHEMBL8292283 | 0.80 | CYP2D6 (0.68) | HTR1ACYP2D6KMT2AMTNR1AMTNR1B | |
| SCHEMBL10674520 | 0.79 | ALDH1A1 (0.85) | HTR1ACYP2D6KMT2ACYP1A2MEN1 | |
| SCHEMBL10670286 | 0.79 | MTNR1A (0.71) | HTR1ACYP2D6KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |