SCHEMBL10679490

SCHEMBL10679490

C=CCNC(CCC)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
CHRM1 P11229 1/20 0.40
AKR1A1 P14550 1/20 0.40
CHRM3 P20309 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
FPR2 P25090 1/20 0.40
FAAH O00519 1/20 0.37
NOD1 Q9Y239 2/20 0.33
MME P08473 1/20 0.33
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33
GGT1 P19440 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9811519 0.89 ALDH1A1 (0.46) ALDH1A1HDAC2FAAHNOD1ACHE
SCHEMBL11217895 0.87 ALDH1A1 (0.51) ALDH1A1FAAHNOD1GRIK1SLC1A2
SCHEMBL3160513 0.86 ALDH1A1 (0.50) ALDH1A1FAAHNOD1MAPT
SCHEMBL614517 0.84 ALDH1A1 (0.36) ALDH1A1FAAHMAPTSMN1; SMN2HPGD
SCHEMBL16703745 0.81 FOLH1 (0.34) ALDH1A1GGT1MAPTSMN1; SMN2
SCHEMBL910825 0.81 FOLH1 (0.52) SLC6A3GAA
SCHEMBL16703747 0.81 FOLH1 (0.34) ALDH1A1GGT1MAPTSMN1; SMN2
SCHEMBL30787971 0.81 GGT1 (0.43) ALDH1A1GGT1GRIK1GRIK2MAPT
SCHEMBL910826 0.81 FOLH1 (0.52) SLC6A3GAA
SCHEMBL910807 0.81 FOLH1 (0.52) SLC6A3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277624-A2 A composition comprising the addition product of a vinyl sulfone dye and a secondary amine and process for dyeing a polyamide therewith HOECHST CELANESE CORPORATION (US) 1988-08-10 EP disclosed
US-4762524-A Composition comprising the addition product of a vinyl-sulfone dye and a secondary amine and process for dyeing a polyamide therewith HOECHST CELANESE CORPORATION (US) 1988-08-09 US disclosed
US-4082792-A SECONDARY ALKYL PRIMARY AMINE, ALKENOIC ACID, PRIMARY OR SECONDARY ALCOHOL TEXACO INC. (US) 1978-04-04 US disclosed
US-3976682-A ALKYLAMMONIUM ALKYLAMINOALKANOATES, FREEZE-THAW ADDITIVE, CORROSION INHIBITOR, PIGMENT GRINDING TEXACO INC. (US) 1976-08-24 US disclosed