Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469309 | 0.85 | L3MBTL1 (0.59) | L3MBTL1MAPK1USP2HSD17B10MAPT | |
| SCHEMBL10678266 | 0.81 | HSD17B10 (0.51) | L3MBTL1MAPK1USP2HSD17B10MAPT | |
| SCHEMBL7464304 | 0.78 | L3MBTL1 (0.42) | L3MBTL1MAPK1USP2HSD17B10MAPT | |
| SCHEMBL10679574 | 0.78 | HSD17B10 (0.49) | L3MBTL1MAPK1USP2HSD17B10MAPT | |
| SCHEMBL9155928 | 0.77 | PARP1 (0.51) | MAPK1USP2HSD17B10MAPTGAA | |
| SCHEMBL10676692 | 0.75 | HTR7 (0.52) | MAPK1USP2HSD17B10MAPTHTT | |
| SCHEMBL17027157 | 0.74 | BRD4 (0.54) | L3MBTL1MAPK1USP2HSD17B10MAPT | |
| SCHEMBL7000081 | 0.74 | PARP1 (0.55) | ACE2JUNNFKB1NFKB2RELA | |
| SCHEMBL10679263 | 0.72 | ALDH1A1 (0.39) | L3MBTL1MAPK1USP2MAPTGAA | |
| SCHEMBL4971050 | 0.71 | BRD4 (0.44) | USP2HSD17B10MAPTHTTACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789675-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0233728-A1 | 1,4-Benzoxazine derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-26 | — | — | EP | disclosed |