Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.67 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.67 |
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090418 | 0.95 | HRH3 (0.73) | HRH3KCNH2HRH4HRH1 | |
| SCHEMBL10679192 | 0.86 | HRH3 (0.69) | HRH3KCNH2HRH4LTA4H | |
| SCHEMBL10679417 | 0.83 | HRH3 (0.97) | HRH3KCNH2HRH4HRH1LTA4H | |
| SCHEMBL10676754 | 0.81 | HRH3 (0.97) | HRH3KCNH2HRH4HRH1LTA4H | |
| SCHEMBL492265 | 0.81 | HRH3 (0.97) | HRH3KCNH2HRH4HRH1LTA4H | |
| SCHEMBL11022798 | 0.81 | CYP2D6 (0.71) | HRH3 | |
| SCHEMBL5857700 | 0.80 | HRH3 (0.94) | HRH3KCNH2HRH4HRH1LTA4H | |
| SCHEMBL13246342 | 0.79 | HRH3 (0.71) | HRH3 | |
| SCHEMBL491672 | 0.79 | HRH3 (0.79) | HRH3KCNH2HRH4HRH1LTA4H | |
| SCHEMBL4849189 | 0.78 | CYP2D6 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792570-A | 3- and 4-biphenyloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |