Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679697 | 0.86 | HRH3 (0.68) | HRH3LTA4HKCNH2HRH4 | |
| SCHEMBL491712 | 0.83 | HRH3 (0.97) | HRH3KDM4ELTA4HBACE1KCNH2 | |
| SCHEMBL5858684 | 0.82 | HRH3 (0.95) | HRH3KDM4ELTA4HBACE1KCNH2 | |
| SCHEMBL28893423 | 0.81 | NPC1 (0.57) | KDM4EALDH1A1TSHRLTA4HBACE1 | |
| SCHEMBL4090418 | 0.81 | HRH3 (0.73) | HRH3KCNH2HRH4 | |
| SCHEMBL10675309 | 0.80 | RAB9A (0.61) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL10682261 | 0.80 | HTR7 (0.44) | HRH3ALDH1A1BACE1 | |
| SCHEMBL21462645 | 0.80 | HRH3 (0.86) | HRH3KDM4EALDH1A1LTA4HBACE1 | |
| SCHEMBL10672109 | 0.79 | HTR7 (0.54) | ALDH1A1TSHR | |
| SCHEMBL12660177 | 0.79 | KDM4E (0.91) | HRH3KDM4EALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792570-A | 3- and 4-biphenyloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |