Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 5/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291189 | 0.89 | ADRB1 (0.72) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| SCHEMBL30656303 | 0.81 | ADRB1 (0.62) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| SCHEMBL173027 | 0.81 | ADRB1 (0.62) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| SCHEMBL10118836 | 0.80 | ADRB1 (0.61) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| SCHEMBL329301 | 0.80 | ADRB1 (0.67) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| SCHEMBL6736376 | 0.79 | ADRB1 (0.60) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28721086 | 0.79 | ADRB1 (0.60) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| SCHEMBL18408991 | 0.79 | ADRB1 (0.60) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| SCHEMBL11206795 | 0.79 | ADRB1 (0.60) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 | |
| SCHEMBL28587090 | 0.79 | ADRB1 (0.60) | ADRB1LMNAMCOLN3AKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775757-A | CARDIOTONIC AND RENAL VASODILATING AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-10-04 | — | — | US | disclosed |