Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656303 | 0.91 | ADRB1 (0.62) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL173027 | 0.91 | ADRB1 (0.62) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL329301 | 0.90 | ADRB1 (0.67) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL10118836 | 0.90 | ADRB1 (0.61) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL10679708 | 0.89 | ADRB1 (0.60) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL11206795 | 0.89 | ADRB1 (0.60) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL28587090 | 0.89 | ADRB1 (0.60) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL6736376 | 0.89 | ADRB1 (0.60) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL18408991 | 0.89 | ADRB1 (0.60) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA | |
| Ammonia Solution, Strong SCHEMBL28721086 | 0.89 | ADRB1 (0.60) | ADRB1ALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281773-A1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-10-05 | — | — | US | disclosed |
| US-9675697-B2 | BET bromodomain inhibitors and therapeutic methods using the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-06-13 | — | — | US | disclosed |
| EP-2265679-B1 | FLUOROCARBON POLYMER COATING COMPOSITIONS | PPG IND OHIO INC (US) | 2017-03-22 | — | — | EP | disclosed |
| CN-102516172-B | 2, 3, 4, 7-tetrahydro-1H-nitrogen azepine compound and preparation method and application thereof | UNIV CHINA AGRICULTURAL | 2013-09-04 | — | — | CN | disclosed |
| US-20090258990-A1 | FLUOROCARBON POLYMER COMPOSITIONS CAPABLE OF PRODUCING LOW GLOSS COATINGS AND METHODS OF COATING COILS THEREWITH | PPG INDUSTRIES OHIO, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-20090258987-A1 | FLUOROCARBON POLYMER COMPOSITIONS AND METHODS OF COATING COILS THEREWITH | PPG INDUSTRIES OHIO, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| WO-2004050606-A1 | PROCESS FOR THE SYNTHESIS OF N-SUBSTITUTED β-AMINO NITRILES THROUGH THE RING OPENING OF AZIRIDINES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-06-17 | — | — | WO | disclosed |
| US-4788108-A | PHOTOPOLYMERIZATION | PPG INDUSTRIES, INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0158874-B1 | CURABLE IMINATED RESINS FROM AMINOPLASTS AND HYDROXYLCONTAINING CARBOXYLIC ACIDS | PPG INDUSTRIES, INC. (US) | 1988-06-08 | — | — | EP | disclosed |
| EP-0158874-A2 | Curable iminated resins from aminoplasts and hydroxylcontaining carboxylic acids | PPG INDUSTRIES, INC. (US) | 1985-10-23 | — | — | EP | disclosed |
| US-4293457-A | POLYESTER; AMINOPLAST CURING AGENT; THERMOPLASTIC ACRYLIC POLYMER; CELLULOSE ACETATE BUTYRATE, EPOXY RESIN, OR VINYL ESTER-VINYL HALIDE COPOLYMER | PPG INDUSTRIES, INC. (US) | 1981-10-06 | — | — | US | disclosed |
| US-4232090-A | Sealerless primers | PPG INDUSTRIES, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4187258-A | AMINOPLAST CURING AGENT; POLYESTER, POLYETHER, OR POLYURETHANE, THERMOPLASTIC ACRYLIC RESIN | PPG INDUSTRIES, INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-3966667-A | Preparation of non-aqueous thermosetting acrylic polymer dispersions | PPG INDUSTRIES, INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3963703-A | Trialkylammonium -N-[β(1-aziridinyl)] propionoylimines | ASHLAND OIL, INC. (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281773-A1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | BRD4, BRDT, BRD3 | ADRB1 3674/4885ALDH1A1 4162/4885HPGD 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.