Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.63 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | CCR3 | P51677 | 2/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616169 | 0.95 | CARM1 (0.62) | CARM1PRMT6BCHESIGMAR1CCR3 | |
| SCHEMBL30616166 | 0.89 | SIGMAR1 (0.57) | CARM1PRMT6SIGMAR1CCR3 | |
| SCHEMBL8238364 | 0.85 | BCHE (0.70) | CARM1PRMT6BCHECCR3 | |
| SCHEMBL10684393 | 0.85 | BCHE (0.70) | CARM1PRMT6BCHECCR3 | |
| SCHEMBL9912161 | 0.84 | PRMT6 (0.68) | CARM1PRMT6BCHECCR3 | |
| SCHEMBL30616175 | 0.83 | CARM1 (0.51) | CARM1PRMT6SIGMAR1CCR3 | |
| SCHEMBL7248339 | 0.83 | CARM1 (0.70) | CARM1PRMT6BCHESIGMAR1CCR3 | |
| SCHEMBL24076365 | 0.81 | CARM1 (0.68) | CARM1PRMT6BCHESIGMAR1CCR3 | |
| Bromide SCHEMBL7247812 | 0.81 | CARM1 (0.68) | CARM1PRMT6BCHESIGMAR1CCR3 | |
| SCHEMBL12658795 | 0.81 | BCHE (0.64) | CARM1PRMT6BCHECCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780478-A | Aminopropoxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 1988-10-25 | — | — | US | disclosed |
| US-4508732-A | Basic ethers useful as antidepressant agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-02 | — | — | US | disclosed |
| EP-0031885-B1 | BASIC ETHERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | MERCK PATENT GmbH (DE) | 1984-06-27 | — | — | EP | disclosed |
| US-4376123-A | Hexahydroazepinyloxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-03-08 | — | — | US | disclosed |
| EP-0031885-A1 | Basic ethers, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1981-07-15 | — | — | EP | disclosed |