Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 12/20 | 0.45 |
| ▸ | CA2 | P00918 | 12/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680323 | 0.84 | JAK2 (0.50) | CHKATRPV1MAPTLMNAADRB2 | |
| SCHEMBL27953545 | 0.78 | CA1 (0.60) | CA1CA2CA12CA9 | |
| SCHEMBL10680303 | 0.78 | CA2 (0.66) | CHKACA1CA2CA12CA9 | |
| SCHEMBL1487309 | 0.78 | CHKA (0.55) | CHKACA1CA2CA12CA9 | |
| SCHEMBL28933199 | 0.77 | CA1 (0.44) | CA1CA2CA12CA9MAPT | |
| SCHEMBL10682397 | 0.74 | TRPV1 (0.59) | CHKATRPV1MAPTCYP1A2CYP2C19 | |
| SCHEMBL28112415 | 0.74 | CHKA (0.80) | CHKATRPV1MAPTLMNAADRB2 | |
| SCHEMBL3440129 | 0.74 | CHKA (0.55) | CHKATRPV1MAPTADRB2NCF1 | |
| SCHEMBL3440130 | 0.73 | CHKA (0.50) | CHKATRPV1MAPTADRB2NCF1 | |
| SCHEMBL9513748 | 0.72 | JAK2 (0.51) | MAPTLMNAADRB2CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788196-A | Phenyl piperazine anti-arrhythmia agents | PFIZER INC. (US) | 1988-11-29 | — | — | US | disclosed |