Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683068 | 1.00 | KDM4E (0.53) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL10684002 | 0.86 | LMNA (0.57) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL10683993 | 0.86 | LMNA (0.57) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11212338 | 0.84 | KDM4E (0.60) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11108009 | 0.82 | LMNA (0.57) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| Water SCHEMBL10675653 | 0.81 | KDM4E (0.56) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL8865302 | 0.80 | KDM4E (0.55) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL10676765 | 0.80 | KDM4E (0.55) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL10683098 | 0.80 | ESR1 (0.43) | KDM4ELMNAESR1ELANEPTGS1 | |
| SCHEMBL10683095 | 0.80 | ESR1 (0.43) | KDM4ELMNAESR1ELANEPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746736-A | THIENAMYCINS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| US-4732977-A | BACTERICIDES | BRISTOL MYERS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| US-4644061-A | Carbapenem antibiotics | BRISTOL-MYERS COMPANY (US) | 1987-02-17 | — | — | US | disclosed |