Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683095 | 1.00 | ESR1 (0.43) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL10682791 | 0.85 | ESR1 (0.44) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL21081301 | 0.84 | ESR1 (0.48) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL10440288 | 0.84 | ESR1 (0.48) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL10679749 | 0.82 | CACNA1C (0.42) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL10679752 | 0.82 | CACNA1C (0.42) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL10440442 | 0.80 | ESR1 (0.44) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL10683072 | 0.80 | KDM4E (0.53) | ESR1PTGS1PDE4AKDM4ELMNA | |
| SCHEMBL10683068 | 0.80 | KDM4E (0.53) | ESR1PTGS1PDE4AKDM4ELMNA | |
| SCHEMBL10679836 | 0.79 | ESR1 (0.43) | ESR1PTGS1PDE4ACACNA1CABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746736-A | THIENAMYCINS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| US-4732977-A | BACTERICIDES | BRISTOL MYERS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| US-4644061-A | Carbapenem antibiotics | BRISTOL-MYERS COMPANY (US) | 1987-02-17 | — | — | US | disclosed |