Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 11/20 | 0.68 |
| ▸ | GSR | P00390 | 1/20 | 0.61 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 2/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272086 | 1.00 | BHMT (0.68) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL7272081 | 1.00 | BHMT (0.68) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL19800862 | 0.90 | BHMT (0.75) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL19800864 | 0.90 | BHMT (0.75) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL7271061 | 0.88 | BHMT (0.66) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL7271063 | 0.88 | BHMT (0.66) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL10683004 | 0.88 | BHMT (0.66) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL1031686 | 0.87 | BHMT (0.76) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL1031684 | 0.87 | BHMT (0.76) | BHMTGSRBHMT2NOS2NOS3 | |
| SCHEMBL21851894 | 0.87 | BHMT (0.76) | BHMTGSRBHMT2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9879043-B1 | Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2018-01-30 | — | — | US | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |