Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068275 | 0.89 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1068583 | 0.87 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8461587 | 0.83 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1066392 | 0.83 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1064311 | 0.82 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1066801 | 0.81 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1065664 | 0.77 | TSHR (0.37) | TSHRHPGDTHRB | |
| SCHEMBL1066701 | 0.76 | THRB (0.38) | TSHRHPGDALDH1A1THRB | |
| SCHEMBL1068323 | 0.75 | TSHR (0.38) | TSHRHPGDTHRB | |
| SCHEMBL1067123 | 0.75 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829142-B2 | Curable composition and process for production of organosilicon compound | TOAGOSEI CO., LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| EP-2270070-B1 | CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND | TOAGOSEI CO LTD (JP) | 2014-07-30 | — | — | EP | disclosed |
| EP-2565217-B1 | Curable composition and process for production of organosilicon compound | TOAGOSEI CO LTD (JP) | 2014-05-14 | — | — | EP | disclosed |
| US-20130149455-A1 | CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND | TOAGOSEI CO., LTD. (JP) | 2013-06-13 | — | — | US | disclosed |
| EP-2565217-A1 | Curable composition and process for production of organosilicon compound | TOAGOSEI CO., LTD. (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20110071255-A1 | CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND | TOAGOSEI CO., LTD. (JP) | 2011-03-24 | — | — | US | disclosed |
| EP-2270070-A1 | CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND | Toagosei Co., Ltd (JP) | 2011-01-05 | — | — | EP | disclosed |