SCHEMBL8461587

SCHEMBL8461587

C=CC(=O)OC(C)[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 3/20 0.33
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8458243 0.90 TSHR (0.51) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2476564 0.86 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1064311 0.85 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1068334 0.83 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1068275 0.82 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2546706 0.81 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27827373 0.79 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28882898 0.78 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16536505 0.77 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27806787 0.77 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110320746-B Radiation-sensitive composition, cured film, method for producing same, display element, and display device JSR株式会社 2024-09-06 CN disclosed
CN-113444373-B Composition for modifying asphalt, modified asphalt, method for producing same, and asphalt mixture 李威风 2023-01-24 CN disclosed
CN-108300385-B Adhesive sheet, display, and method for producing same 琳得科株式会社 2022-02-15 CN disclosed
CN-113444373-A Composition for modifying asphalt, modified asphalt, method for producing same, and asphalt mixture 李威风 2021-09-28 CN disclosed
EP-0604677-B1 Method of making coated shaped articles MITSUBISHI RAYON CO (JP) 1999-08-11 EP disclosed
US-5470616-A Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1995-11-28 US disclosed
EP-0604677-A1 Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1994-07-06 EP disclosed