SCHEMBL106834

SCHEMBL106834

CCCC(=O)C(=O)C(C)C

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 7/20 0.58
CES1 P23141 7/20 0.58
HDAC3 O15379 4/20 0.46
HDAC1 Q13547 4/20 0.46
HDAC2 Q92769 4/20 0.46
HDAC8 Q9BY41 4/20 0.46
FFAR3 O14843 3/20 0.46
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 2/20 0.37
HDAC6 Q9UBN7 1/20 0.36
CYP3A4 P08684 1/20 0.35
NFKB1 P19838 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CTSD P07339 1/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6061322 0.84 CES1 (0.62) CES2CES1ALDH1A1LMNACA1
SCHEMBL27549712 0.82 CES2 (0.64) CES2CES1TSHRALDH1A1LMNA
SCHEMBL8536724 0.82 CES1 (0.59) CES2CES1ALDH1A1LMNACA1
SCHEMBL28294448 0.80 CES2 (0.65) CES2CES1TSHRALDH1A1LMNA
SCHEMBL108932 0.79 CES2 (0.52) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL9362108 0.78 CES1 (0.58) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL105950 0.77
SCHEMBL10308350 0.76 CA1 (0.33) CA1
SCHEMBL108642 0.75 CES1 (1.00) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL13967825 0.74 CES2 (0.52) CES2CES1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461147-A Curing catalyst and resin composition 广荣化学株式会社 2022-12-09 CN claimed
CN-112088336-A Composition for forming resist underlayer film and pattern forming method 三菱瓦斯化学株式会社 2020-12-15 CN claimed
CN-112041705-A Optical component-forming composition and cured product thereof 三菱瓦斯化学株式会社 2020-12-04 CN claimed
CN-112005168-A Resist underlayer film forming composition, underlayer film for lithography, and pattern forming method 三菱瓦斯化学株式会社 2020-11-27 CN claimed
CN-111164511-A Composition for lithography, pattern formation method, and compound 学校法人关西大学 2020-05-15 CN claimed
CN-107474826-A Red iridium phosphor material, its preparation method and the application of a kind of Nitrogen-Containing Heterocyclic Ligand 烟台显华化工科技有限公司 2017-12-15 CN claimed
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
EP-2195440-A2 BIOFUEL PRODUCTION Bio Architecture Lab, Inc. (US) 2010-06-16 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
CN-118234772-A Curable composition, cured product, and catalyst for curing blocked isocyanate compound 广荣化学株式会社 2024-06-21 CN disclosed
US-5834151-A EXPOSING IMAGING LAYER TO FORM MIRROR IMAGE USING THERMAL TRANSFER; HEAT SENSITIVE RECORDING KONICA CORPORATION (JP) 1998-11-10 US disclosed
EP-0798129-A1 Image forming method KONICA CORPORATION (JP) 1997-10-01 EP disclosed
WO-1997028135-A1 2,3-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS AMPA-RECEPTOR INHIBITORS SCHERING AKTIENGESELLSCHAFT (DE) 1997-08-07 WO disclosed
US-4180386-A ANTIKNOCK FUEL ADDITIVES E. I. DU PONT DE NEMOURS & COMPANY (US) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA CES2 60/4885CES1 73/4885HDAC3 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.