SCHEMBL28294448

SCHEMBL28294448

CCCCCCC(=O)C(=O)C(C)C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.65
CES1 P23141 4/20 0.65
LMNA P02545 2/20 0.55
PLA2G2A P14555 4/20 0.53
PLA2G5 P39877 3/20 0.53
PPARG P37231 4/20 0.50
PPARD Q03181 4/20 0.50
PPARA Q07869 4/20 0.50
TSHR P16473 3/20 0.50
GPR84 Q9NQS5 3/20 0.50
HDAC11 Q96DB2 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
TLR2 O60603 1/20 0.50
FAAH O00519 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27549712 0.98 CES2 (0.64) CES2CES1LMNAPLA2G2APLA2G5
SCHEMBL8536724 0.93 CES1 (0.59) CES2CES1LMNAPLA2G2APLA2G5
SCHEMBL6061322 0.91 CES1 (0.62) CES2CES1LMNAPLA2G2APLA2G5
SCHEMBL8680600 0.81 CA1 (0.59) CES2CES1LMNAGPR84MEN1
SCHEMBL7628357 0.81 CA1 (0.59) CES2CES1LMNAGPR84MEN1
SCHEMBL28241003 0.80 CES2 (0.58) CES2CES1TSHRALDH1A1
SCHEMBL7626916 0.80 CES2 (1.00) CES2CES1PPARGPPARDPPARA
SCHEMBL1286262 0.80 CES2 (1.00) CES2CES1PPARGPPARDPPARA
SCHEMBL22110987 0.80 CES2 (1.00) CES2CES1PPARGPPARDPPARA
SCHEMBL1692355 0.80 CES2 (1.00) CES2CES1PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207733-B Novel crosslinking catalysts for silicone compositions 埃肯有机硅法国简易股份公司 2020-07-14 CN claimed
CN-107001634-B Crosslinking catalysts for silicone compositions 埃肯有机硅法国简易股份公司 2020-04-24 CN claimed
CN-114846049-B Nonaqueous crosslinkable compositions 湛新荷兰有限公司 2024-05-24 CN disclosed
CN-113544181-B Non-aqueous crosslinkable compositions 湛新荷兰有限公司 2023-08-08 CN disclosed
CN-114846049-A Non-aqueous crosslinkable compositions 湛新荷兰有限公司 2022-08-02 CN disclosed
CN-111247193-B Method for producing organopolysiloxane, radiation-curable organopolysiloxane composition, and release sheet 信越化学工业株式会社 2022-04-12 CN disclosed
CN-107207733-B Novel crosslinking catalysts for silicone compositions 埃肯有机硅法国简易股份公司 2020-07-14 CN disclosed
CN-111247193-A Method for producing radical polymerizable organopolysiloxane, radiation curable organopolysiloxane composition, and release sheet 信越化学工业株式会社 2020-06-05 CN disclosed
CN-107001634-B Crosslinking catalysts for silicone compositions 埃肯有机硅法国简易股份公司 2020-04-24 CN disclosed
CN-109776293-A A method of 1,3- cyclohexadione compounds are prepared with acetylenic ketone 温州大学 2019-05-21 CN disclosed