Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTAFR | P25105 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498351 | 0.94 | PKM (0.45) | CA2PKMPOLBGAAGFER | |
| SCHEMBL9497465 | 0.88 | PKM (0.51) | CA2PKMPOLBGAAPTAFR | |
| SCHEMBL15044689 | 0.86 | MEN1 (0.46) | CA2TSHRSMN1; SMN2PTAFRGLA | |
| SCHEMBL9151797 | 0.84 | PKM (0.60) | CA2PKMPOLBGAAPTAFR | |
| SCHEMBL10895034 | 0.84 | CA2 (0.49) | CA2PKMGAATSHRPTAFR | |
| SCHEMBL11311830 | 0.84 | PKM (0.39) | CA2PKMPOLBGAAGFER | |
| SCHEMBL9811333 | 0.82 | CA2 (0.53) | CA2TSHRCYP1A2CA1 | |
| SCHEMBL10686038 | 0.82 | CA2 (0.49) | CA2POLBTSHRCYP1A2CA1 | |
| SCHEMBL9150135 | 0.82 | PKM (0.49) | CA2PKMPOLBGAAPTAFR | |
| SCHEMBL17779178 | 0.81 | PKM (0.51) | CA2PKMPOLBGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746323-A | SYNERGISTIC | HOECHST CELANESE CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |