Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PGK1 | P00558 | 2/20 | 0.43 |
| ▸ | PGK2 | P07205 | 2/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16253828 | 0.88 | PGK1 (0.52) | PGK1PGK2PTPN5 | |
| Phosphoric Acid SCHEMBL8578561 | 0.79 | CYP19A1 (0.55) | TSHRLMNAPGK1PGK2PTPN5 | |
| SCHEMBL9496455 | 0.79 | PGK1 (0.44) | TSHRLMNAPGK1PGK2ALDH1A1 | |
| SCHEMBL3977504 | 0.78 | PGK1 (0.40) | PGK1PGK2CYP19A1 | |
| SCHEMBL11759829 | 0.77 | TSHR (0.48) | TSHRLMNAPGK1PGK2PTPN5 | |
| SCHEMBL3883723 | 0.77 | TSHR (0.48) | TSHRLMNAPGK1PGK2PTPN5 | |
| SCHEMBL14029162 | 0.77 | TSHR (0.48) | TSHRLMNAPGK1PGK2PTPN5 | |
| Water SCHEMBL5163061 | 0.77 | PGK1 (0.43) | TSHRLMNAPGK1PGK2ALDH1A1 | |
| SCHEMBL4094823 | 0.77 | FDPS (0.53) | TSHRLMNAPGK1PGK2PTPN5 | |
| SCHEMBL4094309 | 0.77 | TSHR (0.54) | TSHRPGK1PGK2CYP19A1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4747966-A | DIPHOSPHONIC ACID, SEQUESTERING AGENT | LION CORPORATION (JP) | 1988-05-31 | — | — | US | claimed |
| US-4747966-A | DIPHOSPHONIC ACID, SEQUESTERING AGENT | LION CORPORATION (JP) | 1988-05-31 | — | — | US | disclosed |