Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.64 |
| ▸ | HRH1 | P35367 | 4/20 | 0.64 |
| ▸ | DRD3 | P35462 | 4/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | MLNR | O43193 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676648 | 0.92 | ADRA1A (0.73) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| Cadaverine Tartrate SCHEMBL10799297 | 0.88 | ADRA1A (0.68) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| Cadaverine Tartrate SCHEMBL10675929 | 0.88 | ADRA1A (0.68) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| SCHEMBL10680817 | 0.87 | CYP3A4 (0.67) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| SCHEMBL10683725 | 0.85 | ADRA1A (0.76) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| SCHEMBL10683605 | 0.84 | SLC29A1 (0.68) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| SCHEMBL10686081 | 0.82 | SLC29A1 (0.59) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| Hydrochloric Acid SCHEMBL10675752 | 0.82 | ADRA1A (0.71) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| Mioflazine SCHEMBL124029 | 0.82 | SLC29A1 (0.70) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| SCHEMBL10676097 | 0.81 | ADRA1A (0.70) | HTR2AADRA1AHRH1DRD3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766125-A | N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-23 | — | — | US | disclosed |