Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684505 | 1.00 | HDAC8 (0.48) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL29138776 | 0.85 | MTNR1A (0.51) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL29489353 | 0.83 | MAPT (0.56) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL15913822 | 0.83 | MAPT (0.56) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL3826539 | 0.81 | KDM4E (0.55) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL3252426 | 0.80 | KDM4E (0.40) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL3252422 | 0.80 | KDM4E (0.40) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL9401790 | 0.79 | KDM4E (0.56) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL9401795 | 0.79 | KDM4E (0.56) | HDAC8HDAC6MTNR1AMTNR1BKDM4E | |
| SCHEMBL13938656 | 0.78 | POLB (0.64) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4723031-A | Processes for synthesizing substituted and unsubstituted aminoacetate esters | CHEVRON RESEARCH COMPANY (US) | 1988-02-02 | — | — | US | disclosed |