Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL10685143 | 0.85 | MKNK1 (0.52) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL15699 | 0.80 | F7 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL22748483 | 0.80 | F7 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL2564207 | 0.80 | F7 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL21379799 | 0.80 | HTT (0.42) | PIM1PIM3PIM2THRBHDAC1 | |
| Adenine SCHEMBL23531099 | 0.79 | F7 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL22129922 | 0.79 | F7 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Mercaptopurine Anhydrous SCHEMBL14125532 | 0.79 | F7 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL23859925 | 0.79 | F7 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL11807677 | 0.79 | F7 (0.55) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791055-A | ENZYME-CLEAVABLE BONDS | MILES INC. (US) | 1988-12-13 | — | — | US | disclosed |
| US-4629688-A | CLINICAL ANALYSIS | MILES LABORATORIES, INC. (US) | 1986-12-16 | — | — | US | disclosed |
| US-4492751-A | Heterogenous specific binding assay employing an enzyme substrate as label | MILES LABORATORIES, INC. (US) | 1985-01-08 | — | — | US | disclosed |