Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL17868384 | 0.94 | LMNA (0.50) | MKNK1CYP3A4HTTMAPK1BRD4 | |
| Niacinamide SCHEMBL17868382 | 0.86 | MKNK1 (0.50) | MKNK1CYP3A4HTTMAPK1BRD4 | |
| Niacinamide SCHEMBL10685138 | 0.85 | F7 (0.48) | MKNK1HDAC1HDAC2F7F3 | |
| Niacinamide SCHEMBL17868377 | 0.85 | HDAC1 (0.46) | MKNK1CYP3A4HTTMAPK1BRD4 | |
| Niacinamide SCHEMBL11597779 | 0.82 | MKNK1 (0.47) | MKNK1CYP3A4HTTMAPK1BRD4 | |
| Niacinamide SCHEMBL11707347 | 0.80 | MKNK1 (0.45) | MKNK1HTTBRD4LMNATSHR | |
| Adenine SCHEMBL15700 | 0.80 | PI4KA (0.55) | MKNK1CYP3A4HTTBRD4CYP1A2 | |
| Adenine SCHEMBL22748487 | 0.80 | PI4KA (0.55) | MKNK1CYP3A4HTTBRD4CYP1A2 | |
| Adenine SCHEMBL2564210 | 0.80 | PI4KA (0.55) | MKNK1CYP3A4HTTBRD4CYP1A2 | |
| SCHEMBL10836915 | 0.79 | HTT (0.71) | CYP3A4HTTMAPK1TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791055-A | ENZYME-CLEAVABLE BONDS | MILES INC. (US) | 1988-12-13 | — | — | US | disclosed |
| US-4629688-A | CLINICAL ANALYSIS | MILES LABORATORIES, INC. (US) | 1986-12-16 | — | — | US | disclosed |
| US-4492751-A | Heterogenous specific binding assay employing an enzyme substrate as label | MILES LABORATORIES, INC. (US) | 1985-01-08 | — | — | US | disclosed |
| US-4383031-A | LIGANDS; IMMUNOASSAY; SIMPLIFICATION; DIAGNOSIS/MEDICAL/ | MILES LABORATORIES, INC. (US) | 1983-05-10 | — | — | US | disclosed |
| US-4380580-A | COUPLING, LABELS | MILES LABORATORIES, INC. (US) | 1983-04-19 | — | — | US | disclosed |
| US-4378428-A | Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays | BAKER INSTRUMENTS CORPORATION (US) | 1983-03-29 | — | — | US | disclosed |
| EP-0062277-A1 | A method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays | Baker Instruments Corporation (US) | 1982-10-13 | — | — | EP | disclosed |
| US-4318980-A | Heterogenous specific binding assay employing a cycling reactant as label | MILES LABORATORIES, INC. (US) | 1982-03-09 | — | — | US | disclosed |
| US-4230797-A | NUCLEOTIDE | MILES LABORATORIES, INC. (US) | 1980-10-28 | — | — | US | disclosed |