Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157166 | 0.82 | HTT (0.48) | HTTHDAC1HDAC3HDAC2LMNA | |
| Niacinamide SCHEMBL10685138 | 0.80 | F7 (0.48) | HDAC1HDAC3HDAC2PIM1PIM3 | |
| SCHEMBL8121389 | 0.74 | BRD4 (0.51) | HTTHPGDMEN1KMT2ASTAT3 | |
| SCHEMBL11591966 | 0.71 | LMNA (0.69) | HTTHDAC1HDAC3HDAC2LMNA | |
| SCHEMBL7490888 | 0.71 | HDAC3 (0.46) | HTTHDAC1HDAC3HDAC2LMNA | |
| SCHEMBL3802970 | 0.70 | STAT3 (0.47) | HTTHDAC1HDAC3HDAC2LMNA | |
| SCHEMBL30013868 | 0.70 | STAT3 (0.47) | HTTHDAC1HDAC3HDAC2LMNA | |
| SCHEMBL11591466 | 0.68 | HDAC1 (0.60) | HTTHDAC1HDAC3HDAC2LMNA | |
| SCHEMBL11591085 | 0.68 | HDAC1 (0.60) | HTTHDAC1HDAC3HDAC2LMNA | |
| Niacinamide SCHEMBL10685143 | 0.68 | MKNK1 (0.52) | HTTHDAC1HDAC2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961565-B2 | DNA logic-gated proximity assembly circuit for biochemical sensing | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-03-30 | — | — | US | disclosed |
| US-20190292580-A1 | DNA LOGIC-GATED PROXIMITY ASSEMBLY CIRCUIT FOR BIOCHEMICAL SENSING | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-09-26 | — | — | US | disclosed |