Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446756 | 0.91 | LMNA (0.45) | LMNACES2CES1TSHRALDH1A1 | |
| Ether SCHEMBL7911427 | 0.84 | LMNA (0.46) | LMNACES2CES1TSHRALDH1A1 | |
| Ether SCHEMBL5574743 | 0.82 | LMNA (0.44) | LMNACES2CES1ALDH1A1KDM4E | |
| Ether SCHEMBL1071204 | 0.80 | LMNA (0.41) | LMNACES2CES1TSHRALDH1A1 | |
| Ether SCHEMBL8663300 | 0.80 | LMNA (0.37) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL452704 | 0.79 | LMNA (0.49) | LMNACES2CES1ALDH1A1KDM4E | |
| Ether SCHEMBL11098722 | 0.78 | LMNA (0.40) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL11360041 | 0.77 | LMNA (0.47) | LMNACES2CES1TSHRALDH1A1 | |
| Benzene SCHEMBL28132336 | 0.77 | LMNA (0.53) | LMNACES2CES1TSHRALDH1A1 | |
| SCHEMBL390944 | 0.77 | LMNA (0.53) | LMNACES2CES1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63015807-A | — | — | None | — | — | JP | disclosed |
| JP-S6315807-A | RADIATION-CROSSLINKABLE COMPOSITION | SANNOPUKO KK | 1988-01-22 | — | — | JP | disclosed |
| US-4162274-A | Crosslinkable urethane resins containing vinyl and carboxyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |