Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685183 | 1.00 | HPGD (0.61) | HPGDKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10690338 | 0.84 | PIM1 (0.50) | HPGDKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10690333 | 0.84 | PIM1 (0.50) | HPGDKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10685116 | 0.82 | HPGD (0.47) | HPGDKMT2AMEN1POLBMAOA | |
| SCHEMBL10691674 | 0.80 | HPGD (0.47) | HPGDKMT2AMEN1POLBMAOA | |
| SCHEMBL10691680 | 0.80 | HPGD (0.47) | HPGDKMT2AMEN1POLBMAOA | |
| SCHEMBL1461837 | 0.79 | ALDH1A1 (0.56) | HPGDKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24991950 | 0.78 | HPGD (0.59) | HPGDKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL10687171 | 0.78 | HPGD (0.59) | HPGDKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL10687991 | 0.78 | HPGD (0.47) | HPGDKMT2AMEN1POLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |