Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691680 | 1.00 | HPGD (0.47) | HPGDPIM1PIM2PIM3MAOA | |
| SCHEMBL10688694 | 0.81 | MTNR1A (0.46) | HPGDPOLBMEN1KMT2A | |
| SCHEMBL10685180 | 0.80 | HPGD (0.61) | HPGDPIM1PIM2PIM3MAOA | |
| SCHEMBL10685183 | 0.80 | HPGD (0.61) | HPGDPIM1PIM2PIM3MAOA | |
| SCHEMBL10685146 | 0.79 | PIM1 (0.51) | HPGDPIM1PIM2PIM3MAOA | |
| SCHEMBL10687987 | 0.77 | HPGD (0.47) | HPGDPIM1PIM2PIM3MAOA | |
| SCHEMBL10687991 | 0.77 | HPGD (0.47) | HPGDPIM1PIM2PIM3MAOA | |
| SCHEMBL10685116 | 0.77 | HPGD (0.47) | HPGDPIM1PIM2PIM3MAOA | |
| SCHEMBL10690377 | 0.75 | PPARG (0.50) | MAOBPTPN1KMT2A | |
| SCHEMBL10683320 | 0.73 | PIM1 (0.47) | HPGDPIM1PIM2PIM3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |