Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 17/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683729 | 0.88 | CACNA1F (0.66) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10545931 | 0.88 | CACNA1F (0.62) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10685281 | 0.87 | CACNA1F (0.45) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10546782 | 0.86 | CACNA1F (0.68) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10683749 | 0.83 | GSK3B (0.63) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10412149 | 0.83 | CACNA1F (0.71) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10686828 | 0.83 | CACNA1F (0.74) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10685461 | 0.83 | CACNA1F (0.64) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9160785 | 0.82 | CACNA1F (0.73) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL8520832 | 0.82 | ALDH1A1 (0.47) | POLBKCNH2GSK3BTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284935-A1 | 5-Substituted quinolone- and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1988-10-05 | — | — | EP | claimed |
| EP-0284935-A1 | 5-Substituted quinolone- and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1988-10-05 | — | — | EP | disclosed |