Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356042 | 0.93 | MCL1 (0.45) | MCL1ACMSDHDAC8HDAC6CA12 | |
| SCHEMBL3137217 | 0.85 | MCL1 (0.47) | MCL1ACMSDHDAC8HDAC6CA12 | |
| SCHEMBL29785059 | 0.85 | MCL1 (0.47) | MCL1ACMSDHDAC8HDAC6CA12 | |
| Ammonia Solution, Strong SCHEMBL29226614 | 0.84 | MCL1 (0.46) | MCL1ACMSDHDAC8HDAC6CA12 | |
| SCHEMBL10045891 | 0.83 | EDNRB (0.52) | MCL1ACMSDHDAC8HDAC6CA12 | |
| SCHEMBL25402840 | 0.82 | CD274 (0.61) | MCL1ACMSDCD274 | |
| SCHEMBL27950640 | 0.82 | MAPT (0.49) | MCL1ACMSDHDAC8HDAC6CA12 | |
| SCHEMBL3989676 | 0.82 | HSD17B1 (0.51) | MCL1ACMSDHDAC8HDAC6CA12 | |
| SCHEMBL29732348 | 0.81 | MCL1 (0.47) | MCL1ACMSDHDAC8HDAC6CA12 | |
| SCHEMBL4895432 | 0.81 | MCL1 (0.47) | MCL1ACMSDHDAC8HDAC6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783514-A | Polymeric monoarylcyclobutane compositions | THE DOW CHEMICAL COMPANY (US) | 1988-11-08 | — | — | US | disclosed |