Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785059 | 1.00 | MCL1 (0.47) | MCL1ACMSDCA12CA1CA2 | |
| SCHEMBL27950640 | 0.96 | MAPT (0.49) | MCL1ACMSDCA12CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL29226614 | 0.91 | MCL1 (0.46) | MCL1ACMSDCA12CA1CA2 | |
| SCHEMBL4431843 | 0.89 | MCL1 (0.45) | MCL1ACMSDCA12CA1CA2 | |
| SCHEMBL29732348 | 0.89 | MCL1 (0.47) | MCL1ACMSDCA12CA1CA2 | |
| SCHEMBL4895432 | 0.89 | MCL1 (0.47) | MCL1ACMSDCA12CA1CA2 | |
| SCHEMBL17456243 | 0.88 | MCL1 (0.46) | MCL1ACMSDCA1CA2KDM4E | |
| SCHEMBL10685447 | 0.85 | MCL1 (0.47) | MCL1ACMSDCA12CA1CA2 | |
| SCHEMBL17209294 | 0.83 | MCL1 (0.36) | MCL1ACMSDCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL27551952 | 0.82 | MCL1 (0.38) | MCL1ACMSDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023195346-A1 | ULTRAVIOLET ABSORBENT | 大阪ガスケミカル株式会社 | 2023-10-12 | — | — | WO | disclosed |
| US-20230091908-A1 | FLUORENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND APPLICATION OF SAME | OSAKA GAS CHEMICALS CO., LTD. (JP) | 2023-03-23 | — | — | US | disclosed |
| CN-111253202-A | Fluorene derivative and preparation method and application thereof | 中国科学院化学研究所 | 2020-06-09 | — | — | CN | disclosed |
| US-8318948-B2 | Fluorene derivatives and organic electronic device using the same | LG CHEM, LTD. (KR) | 2012-11-27 | — | — | US | disclosed |
| US-8084559-B2 | Ethylene-vinylcyclohexane copolymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20100071769-A1 | FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2010-03-25 | — | — | US | disclosed |
| US-20080161514-A1 | Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer | SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) | 2008-07-03 | — | — | US | disclosed |
| WO-2008069586-A1 | NEW FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2008-06-12 | — | — | WO | disclosed |
| CN-101107260-A | Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2008-01-16 | — | — | CN | disclosed |
| EP-0666267-B1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-04-18 | — | — | EP | disclosed |
| US-5668230-A | METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5571880-A | CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0666267-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230091908-A1 | FLUORENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND APPLICATION OF SAME | ADORA2B, ADORA2A, ADORA1 | MCL1 1712/4885ACMSD 2835/4885CA12 2606/4885 |
| US-20100071769-A1 | FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | VDAC2, VDAC1, FTO | MCL1 2216/4885ACMSD 1634/4885CA12 4078/4885 |
| US-20080161514-A1 | Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer | AOC2, ACSL1, ACSL3 | MCL1 1513/4885ACMSD 2753/4885CA12 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.